For 20 years medical investigators have been working to find possible ways to better understand the pathological mechanisms underlying scleroderma. Their main objective is to improve treatment and hasten diagnosis. Early detection and treatment may prevent symptoms from worsening. Much progress has been made in the last 20 years, particularly in regard to the mechanisms leading to fibrosis and damaged blood vessels. Thanks to these advances, there has been a steady increase in recent years in the success rate of treatments aimed at reducing disease-related manifestations and relieving pain. Despite all this, it is still impossible to eradicate scleroderma. That is why financial support is so crucial for the continuation of research in scleroderma. Funding by Scleroderma Quebec has allowed for the establishment of the only Scleroderma Research Chair in Canada.